63 Pathology MCQs Answers
on
with
0 comments
You are here: Home » Pathology MCQs » 63 Pathology MCQs Answers
Neuroblastoma is a form of cancer, found primarily in children, that attacks the developing nerve cells. Neuroblastoma is the most common extracranial solid tumor in infants and children, accounting for 6% to 10% of all childhood cancers and 15% of all pediatric cancer deaths in the United States.
- Approximately 30% of primary neuroblastomas demonstrate N-myc amplification, which is strongly correlated with advanced-stage tumors and poor prognosis, independent of patient age and staging
- Nonmorphologic favorable prognostic indicators are age less than 1 year, clinical stages 1, 2, and 4S, and N-myc nonamplification.
- Neuroblastomas arise from primordial neural crest cells, which migrate during embryogenesis to form the adrenal medulla and sympathetic ganglia.
- As a result, neuroblastomas occur in the adrenal medulla or anywhere along the sympathetic ganglia, most notably in the retroperitoneum and posterior mediastinum.
- Plain radiographs and ultrasonography are routinely obtained for patients who have any suspicious mass. Chest radiographs revealing posterior mediastinal mass can narrow the differential diagnoses; calcification is also detected in up to 50% of cases.
Category: Pathology MCQs
Subscribe to:
Post Comments (Atom)
POST COMMENT
0 comments:
Post a Comment