Pharmacology MCQ 393
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Pharmacology MCQ 395
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Pharmacology MCQ 396
Other adverse effects and/or consequences of acute overdose of TCA are:
A. dry skin due to loss of sweating
B. cardiac arrhythmias (A-V) block
C. mania and confusion
D. vomiting
E. retention of urine
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A. dry skin due to loss of sweating
B. cardiac arrhythmias (A-V) block
C. mania and confusion
D. vomiting
E. retention of urine
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Pharmacology MCQ 397
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Pharmacology MCQ 398
Regarding psychoses-neuroleptics are effective against all except:
A. hallucinations and delusions
B. feelings of external control
C. tremor, rigidity of skeletal muscle
D. thought disorders
E. apathy, withdrawal
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A. hallucinations and delusions
B. feelings of external control
C. tremor, rigidity of skeletal muscle
D. thought disorders
E. apathy, withdrawal
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Pharmacology MCQ 399
Phenothiazine group of neuroleptics includes:
A. Flupenthixol
B. Fluspirilen
C. Haloperidol
D. Chlorpromazine
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A. Flupenthixol
B. Fluspirilen
C. Haloperidol
D. Chlorpromazine
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Pharmacology MCQ 400
Phenothiazines can be used for all except
A. treatment of schizophrenia
B. treatment of mania and delirium
C. treatment of malignant neuroleptic syndrome
D. premedication and neuroleptanalgesia in surgery
E. treatment of aggressive and violent behaviour
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A. treatment of schizophrenia
B. treatment of mania and delirium
C. treatment of malignant neuroleptic syndrome
D. premedication and neuroleptanalgesia in surgery
E. treatment of aggressive and violent behaviour
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Pharmacology MCQ 401
Restlessness, agitation and insomnia soon after starting neuroleptics
A. are the signs of a Parkinsonian syndrome
B. are the signs of acute akathisia
C. are the symptoms of aggravated psychosis
D. are the signs of allergy
E. are signs of drug dependence
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A. are the signs of a Parkinsonian syndrome
B. are the signs of acute akathisia
C. are the symptoms of aggravated psychosis
D. are the signs of allergy
E. are signs of drug dependence
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Pharmacology MCQ 402
All of the following are features of Malignant neuroleptic syndrome except
A. is potentionally fatal complication of neuroleptics
B. its clinical feature is muscle rigidity
C. its clinical feature is hypothermia
D. its clinical feature is stupor and coma
E. responds to treatment with dantrolene
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A. is potentionally fatal complication of neuroleptics
B. its clinical feature is muscle rigidity
C. its clinical feature is hypothermia
D. its clinical feature is stupor and coma
E. responds to treatment with dantrolene
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Pharmacology MCQ 403
Pre-existing epilepsy in patients on neuroleptics
A. may be alleviated
B. may be aggravated
C. is not influenced
D. can result in agranulocytosis
E. can result in astrocytoma
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A. may be alleviated
B. may be aggravated
C. is not influenced
D. can result in agranulocytosis
E. can result in astrocytoma
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Pharmacology MCQ 404
Chlorpromazine is useful in all except
A. for treatment of hiccough
B. for treatment of vestibular disorders
C. for prevention of drug induced nausea (premedication in surgery)
D. for treatment of alcoholism
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A. for treatment of hiccough
B. for treatment of vestibular disorders
C. for prevention of drug induced nausea (premedication in surgery)
D. for treatment of alcoholism
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Pharmacology MCQ 405
Thioridazine is characterized by:
A. profoundly sedating
B. much antimuscarinic action
C. high extrapyramidal effect
D. with piperazine side chain in the structure
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A. profoundly sedating
B. much antimuscarinic action
C. high extrapyramidal effect
D. with piperazine side chain in the structure
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Pharmacology MCQ 406
Perphenazine and prochlorperazine are characterized:
A. piperidine side chain in the structure
B. profoundly sedating
C. little antimuscarinic action
D. little extrapyramidal effect
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A. piperidine side chain in the structure
B. profoundly sedating
C. little antimuscarinic action
D. little extrapyramidal effect
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Pharmacology MCQ 407
In comparison to butyrophenones, phenothiazines are generally
A. less sedating
B. more hypotensive
C. less antimuscarinic
D. have more extrapyramidal toxicity
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A. less sedating
B. more hypotensive
C. less antimuscarinic
D. have more extrapyramidal toxicity
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Pharmacology MCQ 408
Antidepressants involve
A. phenothiazines
B. butyrophenones
C. thymoleptics
D. thioxanthenes
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A. phenothiazines
B. butyrophenones
C. thymoleptics
D. thioxanthenes
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Pharmacology MCQ 409
Thymoleptics involve all except
A. benzodiazepines
B. 2nd generation (comprising mianserin, viloxazine and maprotiline)
C. serotonin reuptake inhibitors (SSRI)
D. tricyclic antidepressant (TCA)
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A. benzodiazepines
B. 2nd generation (comprising mianserin, viloxazine and maprotiline)
C. serotonin reuptake inhibitors (SSRI)
D. tricyclic antidepressant (TCA)
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Pharmacology MCQ 410
The main mechanism of the effect of the tricyclic antidepressant is
A. inhibition of extraneuronal uptake
B. inhibition of reuptake of amines by nerve terminals
C. release of amines by nerve terminals
D. inhibition of MAO
E. inhibition of COMT
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A. inhibition of extraneuronal uptake
B. inhibition of reuptake of amines by nerve terminals
C. release of amines by nerve terminals
D. inhibition of MAO
E. inhibition of COMT
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Pharmacology MCQ 411
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The monoaminergic theory suggests that depression results from all of the following exceptA. overstimulation of dopaminergic receptors in the CNS
B. deficient monoaminergic transmission in the CNS
C. deficient norepinephrine and/or 5-HT transmission in the CNS
D. deficient norepinephrine and/or serotonin transmission in the CNS
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Pharmacology MCQ 412
Inhibition of reuptake is established long before depression is alleviated
A. because of the long T 0.5 of amines
B. because of the pre-existing up regulation of the postsynaptic receptors
C. because of the pre-existing down regulation of the postsynaptic receptors
D. because of the rapid metabolism of amines
E. because of the enterohepatic cycle of amines
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A. because of the long T 0.5 of amines
B. because of the pre-existing up regulation of the postsynaptic receptors
C. because of the pre-existing down regulation of the postsynaptic receptors
D. because of the rapid metabolism of amines
E. because of the enterohepatic cycle of amines
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Pharmacology MCQ 413
In addition, TCA‘s block all except:
A. histamine receptors
B. muscarinic receptors
C. 5-HT receptors
D. nicotinic receptors
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A. histamine receptors
B. muscarinic receptors
C. 5-HT receptors
D. nicotinic receptors
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Pharmacology MCQ 414
Blockade of the muscarinic receptors results in all except
A. dry mouth
B. blurred vision, aggravation of narrow-angle glaucoma
C. constipation
D. tachycardia
E. bronchoconstriction
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A. dry mouth
B. blurred vision, aggravation of narrow-angle glaucoma
C. constipation
D. tachycardia
E. bronchoconstriction
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Pharmacology MCQ 415
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All are true regaridng Pimozide exceptA. can potentiate arrhythmogenic toxicity of cardioactive drugs
B. is short-acting
C. serious arrhythmias have been associated with administration of pimozide
D. an ECG must be taken before treatment
E. should be avoided in children
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Pharmacology MCQ 416
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All are true of Clozapine except:A. can be effective in patients who have not responded to other drugs
B. increases risk of cardiac arrhythmias with drugs that prolong QT interval
C. is effective against negative as well as positive symptoms of schizophrenia
D. do not induce neutropenia or agranulocytosis
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