The correct answer is A.
Endo
metrial cancer is the most common gynecologic cancer in women older than 45. There are tens of thousands of new cases every year in the U.S., and thousands of deaths from it yearly.
However, there is no effective screening test for endometrial cancer at this point. It is not cost-effective to screen asymptomatic women for endometrial cancer. Occasionally, a Pap test will detect abnormal endometrial cells, but it is not a proper screening tool for endometrial cancer. Patients with endometrial hyperplasia or cancer often present with irregular uterine bleeding. Therefore, patients with irregular uterine bleeding should be considered for endometrial biopsy or ultrasonic evaluation of the endometrial cavity.
This strategy may be modified for young patients, in whom the risk of endometrial hyperplasia or cancer is limited.
To state that screening is with endometrial biopsy and starts at age 40 (choice B) or age 50 (choice C) is incorrect.
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