Endocrinology MCQ Answer 009
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The correct Answer is F
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The correct Answer is FCategories
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2 comments:
even though thiazides causes hypercalcemia why would we use a diueritic for osteoporosis????
@Anonymous
Though all diuretics can cause hypercalcemia and increased excretion of calcium some such as Thiazide diuretics can paradoxically increase bone density.
The New England Journal of Medicine published, "Thiazide effect on the mineral content of bone". by RD Wasnich, RJ Benfante, K Yano, L Heilbrun and JM Vogel in 1983. This study included 1368 men with a mean age of 68 years. Of these 323 were taking thiazides for hypertension. Thiazide users had significantly more bone mineral content at all sites tested than did non-users.
The authors concluded: "These findings suggest the possibility of a preventive or therapeutic role for thiazides in osteoporosis".
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