Omphalocele and Gastrochisis

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The correct answer is D.


Explanation:

During the fourth week of development, the lateral body folds move ventrally and fuse in the midline to form the anterior body wall. Incomplete fusion results in a defect that allows abdominal viscera to protrude from the abdominal cavity, a condition known as gastroschisis.

Prenatal Diagnosis and Genetic Counseling of Omphalocele: An Overview and Atlas of CasesDuring development, the midgut normally herniates into the umbilical cord and then subsequently retracts into the abdominal cavity. Failure of the intestinal loop to retract from the umbilical cord (choice A) results in omphalocele.

Failure of the yolk stalk to degenerate (choice B) results in an ileal (Meckel's) diverticulum or a vitelline fistula or cyst. In the early embryo, the gut tube is connected to the yolk sac by a narrow connection known as the yolk stalk. Normally, this connection degenerates.

During development, certain peritoneal organs fuse with the posterior abdominal wall to become secondarily retroperitoneal. Failure of this peritoneal fusion (choice C) will result in certain organs that are normally immobile being mobile (e.g., mobile cecum).

Umbilical herniation (choice E) results from abdominal viscera protruding through a weakness in the abdominal wall after development. Such protrusions are covered by subcutaneous fascia and skin, distinguishing them from gastroschisis.

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