Potter's Syndome

The correct answer is D.

Explanation:
The sequence is Potter's syndrome, in which bilateral renal agenesis leads to oligohydramnios (an abnormally low amount of amniotic fluid) because the kidneys do not produce normal amounts of urine, which contributes to amniotic fluid. Oligohydramnios causes uterine compression of the fetus, which in turn causes limb deformities, breech position, and pulmonary hypoplasia.

Duodenal (choice A) and esophageal (choice B) atresia can cause polyhydramnios, rather than oligohydramnios, since the amniotic fluid cannot be swallowed, but continues to be produced by the kidneys.

The heart (choice C) is not directly involved in Potter's syndrome, although major malformations of the heart may accompany major malformations of the kidneys.

The lungs (choice E) become secondarily hypoplastic as a consequence of inadequate amniotic fluid, rather than as a primary malformation.

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