COMEDK 2007 MCQ Answer 123

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The correct answer is D

Sympathetic Ophthalmia (SO):

  • Rare, bilateral, immune-mediated, mild to severe granulomatous uveitis seen 2 weeks to 3 months (80%) after penetrating trauma or surgery.
  • Scattered, multifocal, yellow-white subretinal infiltrations (Dalen-Fuchs’ nodules, 50%) with overlying serous retinal detachments, vitritis, and papillitis.
  • Associated with inflammation in sympathizing (fellow) eye and worsened inflammation in exciting (injured) eye (keratic precipitates are an ominous sign);
  • may have meningeal signs, poliosis, and alopecia (as in Vogt-Koyanagi-Harada syndrome).
  • Patients have transient obscuration of vision, photophobia, pain, and blurred vision.
  • Male predilection (probably reflects increased incidence of trauma in this group);
  • chronic, recurring course;
  • prognosis good (65% achieve >20/60 vision after treatment);
  • associated with HLA-A11.

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