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COMEDK 2007 MCQ Answer 123
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DSympathetic Ophthalmia (SO):- Rare, bilateral, immune-mediated, mild to severe granulomatous uveitis seen 2 weeks to 3 months (80%) after penetrating trauma or surgery.
- Scattered, multifocal, yellow-white subretinal infiltrations (Dalen-Fuchs’ nodules, 50%) with overlying serous retinal detachments, vitritis, and papillitis.
- Associated with inflammation in sympathizing (fellow) eye and worsened inflammation in exciting (injured) eye (keratic precipitates are an ominous sign);
- may have meningeal signs, poliosis, and alopecia (as in Vogt-Koyanagi-Harada syndrome).
- Patients have transient obscuration of vision, photophobia, pain, and blurred vision.
- Male predilection (probably reflects increased incidence of trauma in this group);
- chronic, recurring course;
- prognosis good (65% achieve >20/60 vision after treatment);
- associated with HLA-A11.
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