MCQ MAHE 2000 Orthopedics Answer 07
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Rheumatoid arthritis (RA) is an inflammation of synovial tissue with symmetric involvement of peripheral joints, hand, feet, and wrists being most commonly affected. RA can also affect nonarticular muscular structures such as tendons, ligaments, and fascia. Occasionally, there are also systemic manifestations such as vasculitis, visceral nodules, Sjogren syndrome, or pulmonary fibrosis present. Pathogenesis results from lymphocytic infiltration and synovial proliferation. Laboratory tests for RA include RA associated nuclear antigen (RANA) and anti-RA-33 autoanitbodies. Diagnostic criteria are listed below:
1. Morning stiffness (>1h)
2. Swelling of three or more joints
3. Swelling of hand joints (prox interphalangeal, metacarpophalyngeal, or wrist)
4. Symmetric joint swelling
5. Subcutaneous nodules
6. Serum Rheumatoid Factor
7. Radiographic evidence of erosions or periarticular osteopenia in hand or wrists
Criteria 1-4 must have been present continuously for 6 weeks or longer and must be observed by a physician. A diagnosis of rheumatoid arthritis requires that 4 of the 7 criteria are fulfilled.
RA occurs in 1% of the population, affecting women 2-3 times more often than men. The most common age of onset is in the 4th to 5th decade, but there exists a distinct juvenile form as well.
Tags: MCQ, Orthopedics, Rheumatoid Arthritis
Category: MAHE 2000 MCQs
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