Adrenal Cortical Adenoma

• Adenomas are circumscribed, discrete tumour. They are usually small, and seldom weigh more than 150 grams.
  
• Cut surface is bright yellow due to lipid-laden tumour cells.
  
• Non-functioning adenomas are more common than functioning (hormonally active) adenomas. Most non-functioning adenomas are clinically silent (unless they are large) and are found incidentally at autopsy.
  
• Functioning cortical adenomas usually hyper-secrete a single hormones, "pure", such as cortisol with resultant.
  
• Cushing's features or aldosterone with hyperaldosteronism.
  
• The combined presence of cortisol and androgen or mineralocorticoid excess suggests the possibility that the tumour may be a cortical carcinoma.

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