National Institute of Occupational Safety and Health

Option D

“A toxic substance is one that demonstrates the potential to induce cancer, tumors, or neoplastic effects in man or experimental animals; to induce a permanent transmissible change in the characteristic of an offspring from those of its human or experimental animal parents; to cause the production of physical defects in the developing human or experimental animal embryo; to produce death in animals exposed via the respiratory tract, skin, eye, mouth or other routes in experimental or domestic animals; to produce irritation or sensitization of the skin, eyes or respiratory passages; to diminish mental alertness, reduce motivation or alter behavior in humans; to adversely affect the health of a normal or disabled person of any age or of either sex by producing reversible or irreversible bodily injury or by endangering life or causing death from exposure via the respiratory tract, skin, eye, mouth or any other route in any quantity, concentration, or dose reported for any length of time”.

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