Answer: Ceftriaxone
The patient has a classic presentation and sputum Gram stain for pneumococcal pneumonia. Patients with respiration rates greater than or equal to 30/min have an increased mortality and should be hospitalized. Ceftriaxone and cefotaxime are active against most Streptococcus pneumoniae isolates. The prevalence of penicillin- and multidrug-resistant pneumococci is increasing.
Ciprofloxacin has indications for pneumococcal pneumonia but is not the first choice for the patient with pneumococcal pneumonia, because the minimal inhibitory concentrations for many pneumococcal pneumonia infections are close to the maximum serum concentrations of ciprofloxacin.
Vancomycin is active against pneumococci, including multidrug-resistant isolates. Restrict vancomycin use for patients in whom alternative therapy is not available to prevent further development of vancomycin-resistant organisms.
The effectiveness of trimethoprim-sulfamethoxazole against pneumococci is decreasing. This patient takes trimethoprim-sulfamethoxazole for prophylaxis and may be more likely to have colonization with resistant S. pneumoniae.
Ceftazidime and ceftizoxime have poor in vitro activity against many isolates (up to 25%) of S. pneumoniae.
(this patient has pneumonia caused by Streptococcus pneumoniae .look at page no.1536 of harri 16, according to the criteria for hospital admission of an adult, this patient should be admitted in hopital for treatment (patient's resp rate is 36/min, o2 saturation --85%).
now, check out the table on page 1535
patients in ward should be treated with cefuroxime/cefotaxime/ceftriaxone.
so, from the options given , the answer shud be ceftriaxone.)
Category:
Infectious Diseases MCQs
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