MCQ Pharmacology Answer 68

The correct answer is D.

While not of major medical concern, urine color changes as a result of medications can be very distressing to patients. These changes are consequently worth learning so that you can warn patients when you prescribe the medicine. Rifampin is a safe drug that is used both for prophylaxis and for active tuberculosis therapy. In addition to discoloring urine, rifampin and its metabolites can discolor feces, saliva, sweat, and tears (and apparently can stain soft contact lenses).

Ethambutol (choice A) is an antituberculosis agent that is added if isoniazid-resistance is suspected and does not alter urine color.

Isoniazid (choice B) remains the principle antituberculosis agent and does not alter urine color.

Pyridoxine (choice C) is used principally in prophylaxis against tuberculosis and does not alter urine color.

Streptomycin (choice E), which must be given intramuscularly, is sometimes used as an adjunctive agent very early in antituberculosis therapy and has sometimes been lifesaving in critically ill patients. It does not cause a urine color change.

Category: Pharmacology MCQs