Pathology MCQ Answer 57

The correct answer is D.

The disease is hairy cell leukemia, which, unlike most forms of leukemia, is characterized by pancytopenia rather than increased numbers of circulating cells. This disease tends to affect older men and the characteristic cells (which are not always obviously "hairy") are positive for tartrate-resistant acid phosphatase (TRAP).
Associate Birbeck granules (choice A) with Langerhans cell histiocytosis (histiocytosis X).
Associate elevated leukocyte alkaline phosphatase (choice B) with myeloid metaplasia.
Associate Philadelphia chromosome (choice C) with chronic myeloid leukemia (and occasionally with acute lymphocytic leukemia).
Associate production of Bence-Jones proteins (choice E) with multiple myeloma.

Category: Pathology MCQs