MCQ Pharmacology Answer 62

The correct answer is E.

Arrow E points to a smooth muscle cell in the media of the arteriole. Alpha1 agonists stimulate alpha1 receptors present on the smooth muscle, which leads to an increase in intracellular calcium via phosphatidylinositol hydrolysis. This increase in calcium is necessary for smooth muscle contraction. Arrow A indicates an endothelial cell located in the intima of the arteriole.

Nitric oxide, also known as endothelial cell relaxing factor (EDRF), is produced from arginine by endothelial cells. A muscarinic agonist can lead to the evolution of NO, producing vasodilatation.

Arrow B indicates a polymorphonuclear leukocyte in the bloodstream.

Arrow C indicates the basal lamina underlying the endothelium.

Arrow D indicates the arteriolar adventitia.

Category: Pharmacology MCQs