MCQ Radiology Answer 19

The correct Answer is B

Explanation: The skeletal changes in thalassaemia are unusual before 6 months of age and the first changes are usually seen in the hands and feet. 'Hair-on-end' appearance can be seen in any form of severe anaemia. Due to extra-medullary haemopoisis, the paranasal sinuses are not developed, except ethmoid air cells due to the absence of the red marrow around them. Iron chelation also causes changes in the skeleton, in the form of meta-epiphyseal dysplasia (one third of patients) and osteoporosis. Distal ulna is one of the earliest site to show dysplastic changes.

References:

1. Tyler PA et al. The radiological appearances in thalassaemia. Clin Rad 2006:61:40-52.
2. Dahnert W. Radiology review manual 5th edition. Lippincott williams and Wilkins 2003: 165-166

Category: Radiology MCQs