MCQ Physiology Answer 7

Lower esophageal sphincter tone is decreased by:

- Pregnancy
- Obesity
- Smoking, Alcohol
- Fatty foods, large meals, chocolate
- Diseases such as diabetes

The lower esophageal sphincter (LES) is a ring of muscle that forms a valve at the lower end of the esophagus, where it joins the stomach.

The LES remains closed except during swallowing, when it allows food to pass from the esophagus into the stomach. When the LES is closed, it prevents the backflow (reflux) of stomach acid into the esophagus. If the LES does not close tightly enough, stomach acid backs up into the esophagus, causing heartburn. A weak lower esophageal sphincter is a major cause of gastroesophageal reflux disease (GERD).

Category: Physiology MCQs