MCQ Hematology Answer 9
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Answer: D
Mast cell disease is associated with irregular and patchy marrow infiltration. The majority of mast cells are the fusiform type and contain a variable number of granules. Fibrosis accompanies mast cell infiltrates. Abundant numbers of eosinophils and foci of reactive lymphocytes are present near the mast cell foci. Uninvolved marrow is usually normal.
Giemsa, toluidine blue, aldehyde-fuschin, astra blue, chloroacetate esterase and tryptase stains are strongly positive in mast cells.
Bain, B.J. Systemic mastocytosis and other mast cell neoplasms. Br. J. Haematol. 1999, 106: 9-17.
Tags: MCQS, Hematology, Mastocytosis
Category: Hematology MCQs
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